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FOXO4
Basic Info. FOXO4 is a transcription factor protein associated with the regulation of cellular senescence, belonging to the FOXO (Forkhead box O) family. It plays a key role in delaying aging, suppressing tumors, and maintaining stem cell function by participating in DNA damage repair, oxidative stress response, and cell cycle regulation. Recent studies have found that targeting. FOXO4-DRI (FOXO4-p53 interfering peptide) can selectively eliminate senescent cells, offering a novel strategy for anti-aging and treating age-related diseases (such as fibrosis and osteoarthritis), with potential biomedical applications. Research on its mechanisms provides important scientific insights for developing anti-aging drugs and cell regeneration therapies. ...
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LL37
Basic Info. LL37 is an antimicrobial peptide with 37 residues, belonging to the humanized cathelicidin family. It has a wide range of antimicrobial activities. such as inhibitory effects on bacterial, fungal, and viral pathogens It is also an immune modulator that participates in the regulation of the immune system ...
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Retatrutide
Basic Info. Retatrutide is an experimental drug developed by Eli Lilly and Company in the United States for the treatment of obesity. It is a triple glucagon hormone receptor agonist. In a phase II clinical trial, the drug has been proved to reduce the average weight of non diabetes but obese or pre obese (overweight) adults by more than 17.5% ...
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melatonin
Basic Info. Melatonin: Understand the Sleep Hormone and Its Benefits Melatonin is a hormone naturally produced in the body, primarily by the pineal gland, that plays a crucial role in regulating the sleep-wake cycle, also known as the circadian rhythm. It helps the body know when to sleep and when to wake up. Melatonin is also available as a supplement, and it is often taken to help with sleep problems, jet lag, and shift work-related sleep disturbances. ...
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HGH Fragment 176-191
Basic Info. The synthetic peptides corresponding to amino acids 172-191, 176-191, 177-191, 178-191, 179-191, and 180-191 of human growth hormone (HGH) have been studied for their in vivo effects in normal rats. Four of the peptides produced a short-lived rise in blood glucose and a more sustained rise in plasma insulin, whereas the other two (HGH 179-191 and 180-191) were inert in the systems tested. A single dose of the peptides containing the amino acids sequence 178-191 of the hGH molecule significantly reduced insulin sensitivity of the animals in intravenous insulin tolerance tests. The findings also indicate that the biologically active peptides must not only have the minimum of the informational sequence but also that this must be in correct physical configuration. ...
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dermorphin
Basic Info. The original source of Dermorphin is Sauvage's leaf frog , Brazilian orange-legged leaf frog, Jandaia leaf frog. Potent and selective natural opioid that binds as an agonist to μ-opioid receptors. 30–40 times more potent than morphine. Antinociceptive effect. Dermorphin is a peptide expressed by the frog venom skin glands with a potent opiate-like activity on mu-type opioid receptors, which have potent depressive and analgesic effects. Dermorphin may also have effects on pulmonary ventilation and pituitary hormone release. Dermorphin is 30-40 times more potent than morphine, however it has never been approved for medical use in humans or animals. ...
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GLP-1, 5mg/vial
Basic Info. GLP-1 agonists are a class of drugs primarily used for managing type 2 diabetes that have also proven to be helpful for supporting weight loss. These medications work by mimicking the actions of the glucagon-like peptide-1 hormone, aiding in blood sugar regulation and promoting a feeling of fullness. ...
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Glutathione
Basic Info. Glutathione is a substance made from the amino acids glycine, cysteine, and glutamic acid. It is produced by the liver and involved in many body processes. Glutathione is involved in tissue building and repair, making chemicals and proteins needed in the body, and in immune system function. ...
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Insulin
Basic Info. Insulin is a peptide hormone secreted by the pancreas that promotes the absorption and utilization of glucose in the liver and muscle tissue, thereby reducing blood sugar levels. The main function of insulin is to help the body convert glucose in food into energy and store it in the liver and muscles ...
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无菌水
Basic Info. Sterile water usually refers to water without bacteria obtained by treating water containing bacteria by physical methods, such as steam method, UHT heat method, ultraviolet sterilization, ozone method and physical filtration method, which kills microorganisms in water and filters it, and the inorganic salts in the water generally do not decrease. ...
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Botulinum toxin
Basic Info. Botulinum toxin, or botulinum neurotoxin, is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum. It's known for its ability to block nerve functions, leading to paralysis and is the cause of the disease botulism. Botulinum toxin is also used in small doses in medical and cosmetic applications, such as Botox injections for wrinkle reduction and other conditions. ...
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5-amino-1MQ
Basic Info. 5-amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT plays a significant role in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as ‘the longevity gene’ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer. ...
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